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CHEK2 1100delC in patients with metachronous cancers of the breast and the colorectum

BACKGROUND: Development of multiple primary tumors is a hallmark of hereditary cancer. At least 1/10 of breast cancers and colorectal cancers occur because of heredity and recently the cell cycle kinase 2, CHEK2 1100delC allele has been identified at a particularly high frequency in families with he...

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Detalles Bibliográficos
Autores principales: Isinger, Anna, Bhat, Misha, Borg, Ake, Nilbert, Mef
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1421428/
https://www.ncbi.nlm.nih.gov/pubmed/16539695
http://dx.doi.org/10.1186/1471-2407-6-64