Selection of antisense oligonucleotides based on multiple predicted target mRNA structures

BACKGROUND: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selection methods are limited by uncertainties in RNA secondary structure prediction. If all the predicted structures of a giv...

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Detalles Bibliográficos
Autores principales: Bo, Xiaochen, Lou, Shaoke, Sun, Daochun, Shu, Wenjie, Yang, Jing, Wang, Shengqi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1421440/
https://www.ncbi.nlm.nih.gov/pubmed/16526963
http://dx.doi.org/10.1186/1471-2105-7-122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1421440/
https://www.ncbi.nlm.nih.gov/pubmed/16526963
http://dx.doi.org/10.1186/1471-2105-7-122

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