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A functional PTPN22 polymorphism associated with several autoimmune diseases is not associated with IgA deficiency in the Spanish population

BACKGROUND: The 1858C/T SNP of the PTPN22 gene has been associated with many autoimmune diseases, suggesting the existence of an inflammatory process common to all of them. We studied the association of that polymorphism with immunoglobulin A deficiency (IgAD) following a double approach: a case-con...

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Detalles Bibliográficos
Autores principales: Núñez, Concepción, López-Mejías, Raquel, Martínez, Alfonso, García-Rodríguez, M Cruz, Fernández-Arquero, Miguel, de la Concha, Emilio G, Urcelay, Elena
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1431514/
https://www.ncbi.nlm.nih.gov/pubmed/16539704
http://dx.doi.org/10.1186/1471-2350-7-25