Computational models with thermodynamic and composition features improve siRNA design

BACKGROUND: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large functional genomics projects. RESULTS: To improve the design of efficient siRNA molecules, we performed a comparative, therm...

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Detalles Bibliográficos
Autores principales: Shabalina, Svetlana A, Spiridonov, Alexey N, Ogurtsov, Aleksey Y
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1431570/
https://www.ncbi.nlm.nih.gov/pubmed/16472402
http://dx.doi.org/10.1186/1471-2105-7-65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1431570/
https://www.ncbi.nlm.nih.gov/pubmed/16472402
http://dx.doi.org/10.1186/1471-2105-7-65

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