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Computational models with thermodynamic and composition features improve siRNA design

BACKGROUND: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large functional genomics projects. RESULTS: To improve the design of efficient siRNA molecules, we performed a comparative, therm...

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Detalles Bibliográficos
Autores principales:	Shabalina, Svetlana A, Spiridonov, Alexey N, Ogurtsov, Aleksey Y
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1431570/ https://www.ncbi.nlm.nih.gov/pubmed/16472402 http://dx.doi.org/10.1186/1471-2105-7-65

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