Structure-Guided Recombination Creates an Artificial Family of Cytochromes P450

Creating artificial protein families affords new opportunities to explore the determinants of structure and biological function free from many of the constraints of natural selection. We have created an artificial family comprising ˜3,000 P450 heme proteins that correctly fold and incorporate a heme...

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Detalles Bibliográficos
Autores principales: Otey, Christopher R, Landwehr, Marco, Endelman, Jeffrey B, Hiraga, Kaori, Bloom, Jesse D, Arnold, Frances H
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1431580/
https://www.ncbi.nlm.nih.gov/pubmed/16594730
http://dx.doi.org/10.1371/journal.pbio.0040112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1431580/
https://www.ncbi.nlm.nih.gov/pubmed/16594730
http://dx.doi.org/10.1371/journal.pbio.0040112

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