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Structure-Guided Recombination Creates an Artificial Family of Cytochromes P450
Creating artificial protein families affords new opportunities to explore the determinants of structure and biological function free from many of the constraints of natural selection. We have created an artificial family comprising ˜3,000 P450 heme proteins that correctly fold and incorporate a heme...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1431580/ https://www.ncbi.nlm.nih.gov/pubmed/16594730 http://dx.doi.org/10.1371/journal.pbio.0040112 |