Antimigraine drug, zolmitriptan, inhibits high-voltage activated calcium currents in a population of acutely dissociated rat trigeminal sensory neurons

BACKGROUND: Triptans, 5-HT(1B/ID )agonists, act on peripheral and/or central terminals of trigeminal ganglion neurons (TGNs) and inhibit the release of neurotransmitters to second-order neurons, which is considered as one of key mechanisms for pain relief by triptans as antimigraine drugs. Although...

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Detalles Bibliográficos
Autores principales: Morikawa, Tomoko, Matsuzawa, Yoshiyasu, Makita, Koshi, Katayama, Yoshifumi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1434723/
https://www.ncbi.nlm.nih.gov/pubmed/16549032
http://dx.doi.org/10.1186/1744-8069-2-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1434723/
https://www.ncbi.nlm.nih.gov/pubmed/16549032
http://dx.doi.org/10.1186/1744-8069-2-10

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