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Increased cholinergic contractions of jejunal smooth muscle caused by a high cholesterol diet are prevented by the 5-HT(4 )agonist – tegaserod

BACKGROUND: Excess cholesterol in bile and in blood is a major risk factor for the respective development of gallbladder disease and atherosclerosis. This lipid in excess negatively impacts the functioning of other smooth muscles, including the intestine. Serotonin is an important mediator of the co...

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Detalles Bibliográficos
Autores principales: Mathison, Ronald, Shaffer, Eldon
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1434748/
https://www.ncbi.nlm.nih.gov/pubmed/16504074
http://dx.doi.org/10.1186/1471-230X-6-8