Neutropenia induced in outbred mice by a simplified low-dose cyclophosphamide regimen: characterization and applicability to diverse experimental models of infectious diseases

BACKGROUND: For its low cost and ease of handling, the mouse remains the preferred experimental animal for preclinical tests. To avoid the interaction of the animal immune system, in vivo antibiotic pharmacodynamic studies often employ cyclophosphamide (CPM) to induce neutropenia. Although high dose...

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Detalles Bibliográficos
Autores principales: Zuluaga, Andres F, Salazar, Beatriz E, Rodriguez, Carlos A, Zapata, Ana X, Agudelo, Maria, Vesga, Omar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1434751/
https://www.ncbi.nlm.nih.gov/pubmed/16545113
http://dx.doi.org/10.1186/1471-2334-6-55

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1434751/
https://www.ncbi.nlm.nih.gov/pubmed/16545113
http://dx.doi.org/10.1186/1471-2334-6-55

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