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Cognitive dysfunction in NF1 knock-out mice may result from altered vesicular trafficking of APP/DRD3 complex

BACKGROUND: It has been estimated that more than 50% of patients with Neurofibromatosis type 1 (NF1) have neurobehavioral impairments which include attention deficit/hyperactivity disorder, visual/spatial learning disabilities, and a myriad of other cognitive developmental problems. The biological m...

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Detalles Bibliográficos
Autores principales: Donarum, Elizabeth A, Halperin, Rebecca F, Stephan, Dietrich A, Narayanan, Vinodh
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1434756/
https://www.ncbi.nlm.nih.gov/pubmed/16524466
http://dx.doi.org/10.1186/1471-2202-7-22