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Zoledronic acid treatment impairs protein geranyl-geranylation for biological effects in prostatic cells

BACKGROUND: Nitrogen-containing bisphosphonates (N-BPs) have been designed to inhibit osteoclast-mediated bone resorption. However, it is now accepted that part of their anti-tumor activities is related to interference with the mevalonate pathway. METHODS: We investigated the effects of zoledronic a...

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Detalles Bibliográficos
Autores principales:	Goffinet, M, Thoulouzan, M, Pradines, A, Lajoie-Mazenc, I, Weinbaum, Carolyn, Faye, JC, Séronie-Vivien, S
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1434759/ https://www.ncbi.nlm.nih.gov/pubmed/16539721 http://dx.doi.org/10.1186/1471-2407-6-60

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