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Reservoir cells no longer detectable after a heterologous SHIV challenge with the synthetic HIV-1 Tat Oyi vaccine

BACKGROUND: Extra-cellular roles of Tat might be the main cause of maintenance of HIV-1 infected CD4 T cells or reservoir cells. We developed a synthetic vaccine based on a Tat variant of 101 residues called Tat Oyi, which was identified in HIV infected patients in Africa who did not progress to AID...

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Detalles Bibliográficos
Autores principales: Watkins, Jennifer D, Lancelot, Sophie, Campbell, Grant R, Esquieu, Didier, Mareuil, Jean de, Opi, Sandrine, Annappa, Sylvie, Salles, Jean-Pierre, Loret, Erwann P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1434768/
https://www.ncbi.nlm.nih.gov/pubmed/16441880
http://dx.doi.org/10.1186/1742-4690-3-8