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Exploring the reasons for the large density of triplex-forming oligonucleotide target sequences in the human regulatory regions

BACKGROUND: DNA duplex sequences that can be targets for triplex formation are highly over-represented in the human genome, especially in regulatory regions. RESULTS: Here we studied using bioinformatics tools several properties of triplex target sequences in an attempt to determine those that make...

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Detalles Bibliográficos
Autores principales: Goñi, Josep Ramon, Vaquerizas, Juan Manuel, Dopazo, Joaquin, Orozco, Modesto
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435886/
https://www.ncbi.nlm.nih.gov/pubmed/16566817
http://dx.doi.org/10.1186/1471-2164-7-63