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Intravenous administration of activated protein C in Pseudomonas-induced lung injury: impact on lung fluid balance and the inflammatory response

BACKGROUND: Acute lung injury (ALI) induces a coagulation/fibrinolysis imbalance and leads to fibrin deposition. The protein C pathway is an important regulator of the coagulation system and reduces the inflammatory response. The aim of the study was to examine the effects of recombinant human activ...

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Detalles Bibliográficos
Autores principales: Robriquet, Laurent, Collet, François, Tournoys, Antoine, Prangère, Thierry, Nevière, Rémi, Fourrier, François, Guery, Benoît P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435891/
https://www.ncbi.nlm.nih.gov/pubmed/16553944
http://dx.doi.org/10.1186/1465-9921-7-41