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NMR solution structures of LNA (locked nucleic acid) modified quadruplexes
We have determined the NMR solution structures of the quadruplexes formed by d(TGLGLT) and d(TL(4)T), where L denotes LNA (locked nucleic acid) modified G-residues. Both structures are tetrameric, parallel and right-handed and the native global fold of the corresponding DNA quadruplex is retained up...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435981/ https://www.ncbi.nlm.nih.gov/pubmed/16614450 http://dx.doi.org/10.1093/nar/gkl144 |