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Polycistronic RNA polymerase II expression vectors for RNA interference based on BIC/miR-155

Vector-based RNA interference (RNAi) has emerged as a valuable tool for analysis of gene function. We have developed new RNA polymerase II expression vectors for RNAi, designated SIBR vectors, based upon the non-coding RNA BIC. BIC contains the miR-155 microRNA (miRNA) precursor, and we find that ex...

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Detalles Bibliográficos
Autores principales: Chung, Kwan-Ho, Hart, Christopher C., Al-Bassam, Sarmad, Avery, Adam, Taylor, Jennifer, Patel, Paresh D., Vojtek, Anne B., Turner, David L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435982/
https://www.ncbi.nlm.nih.gov/pubmed/16614444
http://dx.doi.org/10.1093/nar/gkl143