A Survival-Adjusted Quantal-Response Test for Analysis of Tumor Incidence Rates in Animal Carcinogenicity Studies

In rodent cancer bioassays, groups of animals are exposed to different doses of a chemical of interest and followed for tumor occurrence. The resulting tumor rates are commonly analyzed using a survival-adjusted Cochran-Armitage (CA) trend test. The CA trend test has reasonable power when the tumor-...

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Detalles Bibliográficos
Autores principales: Peddada, Shyamal D., Kissling, Grace E.
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440777/
https://www.ncbi.nlm.nih.gov/pubmed/16581542
http://dx.doi.org/10.1289/ehp.8590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440777/
https://www.ncbi.nlm.nih.gov/pubmed/16581542
http://dx.doi.org/10.1289/ehp.8590

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