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A Survival-Adjusted Quantal-Response Test for Analysis of Tumor Incidence Rates in Animal Carcinogenicity Studies
In rodent cancer bioassays, groups of animals are exposed to different doses of a chemical of interest and followed for tumor occurrence. The resulting tumor rates are commonly analyzed using a survival-adjusted Cochran-Armitage (CA) trend test. The CA trend test has reasonable power when the tumor-...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
National Institute of Environmental Health Sciences
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440777/ https://www.ncbi.nlm.nih.gov/pubmed/16581542 http://dx.doi.org/10.1289/ehp.8590 |