Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease

BACKGROUND: Accumulating evidence suggests that inflammation plays an important role in the progression of Parkinson's disease (PD). Among many inflammatory factors found in the PD brain, cyclooxygenase (COX), specifically the inducible isoform, COX-2, is believed to be a critical enzyme in the...

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Detalles Bibliográficos
Autores principales: Vijitruth, Rattanavijit, Liu, Mei, Choi, Dong-Young, Nguyen, Xuan V, Hunter, Randy L, Bing, Guoying
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440849/
https://www.ncbi.nlm.nih.gov/pubmed/16566823
http://dx.doi.org/10.1186/1742-2094-3-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440849/
https://www.ncbi.nlm.nih.gov/pubmed/16566823
http://dx.doi.org/10.1186/1742-2094-3-6

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