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Algorithm for automatic genotype calling of single nucleotide polymorphisms using the full course of TaqMan real-time data

Single nucleotide polymorphisms (SNPs) are often determined using TaqMan real-time PCR assays (Applied Biosystems) and commercial software that assigns genotypes based on reporter probe signals at the end of amplification. Limitations to the large-scale application of this approach include the need...

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Detalles Bibliográficos
Autores principales: Callegaro, A., Spinelli, R., Beltrame, L., Bicciato, S., Caristina, L., Censuales, S., De Bellis, G., Battaglia, C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440877/
https://www.ncbi.nlm.nih.gov/pubmed/16617143
http://dx.doi.org/10.1093/nar/gkl185