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Algorithm for automatic genotype calling of single nucleotide polymorphisms using the full course of TaqMan real-time data
Single nucleotide polymorphisms (SNPs) are often determined using TaqMan real-time PCR assays (Applied Biosystems) and commercial software that assigns genotypes based on reporter probe signals at the end of amplification. Limitations to the large-scale application of this approach include the need...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440877/ https://www.ncbi.nlm.nih.gov/pubmed/16617143 http://dx.doi.org/10.1093/nar/gkl185 |