Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells

Abasic (AP)-endonuclease (APE) is responsible for repair of AP sites, and single-strand DNA breaks with 3′ blocking groups that are generated either spontaneously or during repair of damaged or abnormal bases via the DNA base excision repair (BER) pathway in both nucleus and mitochondria. Mammalian...

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Detalles Bibliográficos
Autores principales: Chattopadhyay, Ranajoy, Wiederhold, Lee, Szczesny, Bartosz, Boldogh, Istvan, Hazra, Tapas K., Izumi, Tadahide, Mitra, Sankar
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440881/
https://www.ncbi.nlm.nih.gov/pubmed/16617147
http://dx.doi.org/10.1093/nar/gkl177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440881/
https://www.ncbi.nlm.nih.gov/pubmed/16617147
http://dx.doi.org/10.1093/nar/gkl177

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