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Substituent effects on the pairing and polymerase recognition of simple unnatural base pairs

As part of an effort to develop stable and replicable unnatural base pairs, we have evaluated a large number of unnatural nucleotides with predominantly hydrophobic nucleobases. Despite its limited aromatic surface area, a nucleobase analog scaffold that has emerged as being especially promising is...

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Detalles Bibliográficos
Autores principales: Hwang, Gil Tae, Romesberg, Floyd E.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440882/
https://www.ncbi.nlm.nih.gov/pubmed/16617144
http://dx.doi.org/10.1093/nar/gkl049