Cargando…

Novel link between E2F1 and Smac/DIABLO: proapoptotic Smac/DIABLO is transcriptionally upregulated by E2F1

Deregulated expression of E2F1 not only promotes S-phase entry but also induces apoptosis. Although it has been well documented that E2F1 is able to induce p53-dependent apoptosis via raising ARF activity, the mechanism by which E2F induces p53-independent apoptosis remains unclear. Here we report t...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Wei, Jiang, Peng, Miao, Lin, Zhao, Ying, Zhimin, Zhai, Qing, Li, Zhu, Wei-guo, Wu, Mian
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440883/
https://www.ncbi.nlm.nih.gov/pubmed/16617145
http://dx.doi.org/10.1093/nar/gkl150