dUTPase activity is critical to maintain genetic stability in Saccharomyces cerevisiae

We identified a viable allele (dut1-1) of the DUT1 gene that encodes the dUTPase activity in Saccharomyces cerevisiae. The Dut1-1 protein possesses a single amino acid substitution (Gly82Ser) in a conserved motif nearby the active site and exhibits a greatly reduced dUTPase activity. The dut1-1 sing...

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Detalles Bibliográficos
Autores principales: Guillet, Marie, Van Der Kemp, Patricia Auffret, Boiteux, Serge
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440884/
https://www.ncbi.nlm.nih.gov/pubmed/16617146
http://dx.doi.org/10.1093/nar/gkl139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440884/
https://www.ncbi.nlm.nih.gov/pubmed/16617146
http://dx.doi.org/10.1093/nar/gkl139

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