Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine

BACKGROUND: The quaternary isoquinoline alkaloid sanguinarine is receiving increasing attention as a potential chemotherapeutic agent in the treatment of cancer. Previous studies have shown that this DNA-binding phytochemical can arrest a number of different types of transformed cells in G0/G1, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Holy, Jon, Lamont, Genelle, Perkins, Edward
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1444914/
https://www.ncbi.nlm.nih.gov/pubmed/16512916
http://dx.doi.org/10.1186/1471-2121-7-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1444914/
https://www.ncbi.nlm.nih.gov/pubmed/16512916
http://dx.doi.org/10.1186/1471-2121-7-13

Ejemplares similares