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Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine
BACKGROUND: The quaternary isoquinoline alkaloid sanguinarine is receiving increasing attention as a potential chemotherapeutic agent in the treatment of cancer. Previous studies have shown that this DNA-binding phytochemical can arrest a number of different types of transformed cells in G0/G1, and...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1444914/ https://www.ncbi.nlm.nih.gov/pubmed/16512916 http://dx.doi.org/10.1186/1471-2121-7-13 |