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Human cytomegalovirus UL27 is not required for viral replication in human tissue implanted in SCID mice

Inhibition of the human cytomegalovirus UL97 kinase by maribavir is thought to be responsible for the antiviral activity of this compound. Some mutations that confer resistance to maribavir map to UL97, however additional mutations that also confer resistance to the drug were mapped to UL27. These o...

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Detalles Bibliográficos
Autores principales: Prichard, Mark N, Quenelle, Debra C, Bidanset, Deborah J, Komazin, Gloria, Chou, Sunwen, Drach, John C, Kern, Earl R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1448171/
https://www.ncbi.nlm.nih.gov/pubmed/16571131
http://dx.doi.org/10.1186/1743-422X-3-18