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Similarities in the immunoglobulin response and V(H )gene usage in rhesus monkeys and humans exposed to porcine hepatocytes

BACKGROUND: The use of porcine cells and organs as a source of xenografts for human patients would vastly increase the donor pool; however, both humans and Old World primates vigorously reject pig tissues due to xenoantibodies that react with the polysaccharide galactose α (1,3) galactose (αGal) pre...

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Detalles Bibliográficos
Autores principales: Zahorsky-Reeves, Joanne L, Gregory, Clare R, Cramer, Donald V, Patanwala, Insiyyah Y, Kyles, Andrew E, Borie, Dominic C, Kearns-Jonker, Mary K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1448184/
https://www.ncbi.nlm.nih.gov/pubmed/16549031
http://dx.doi.org/10.1186/1471-2172-7-3