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Farnesylation or geranylgeranylation? Efficient assays for testing protein prenylation in vitro and in vivo

BACKGROUND: Available in vitro and in vivo methods for verifying protein substrates for posttranslational modifications via farnesylation or geranylgeranylation (for example, autoradiography with (3)H-labeled anchor precursors) are time consuming (weeks/months), laborious and suffer from low sensiti...

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Detalles Bibliográficos
Autores principales: Benetka, Wolfgang, Koranda, Manfred, Maurer-Stroh, Sebastian, Pittner, Fritz, Eisenhaber, Frank
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1448197/
https://www.ncbi.nlm.nih.gov/pubmed/16507103
http://dx.doi.org/10.1186/1471-2091-7-6