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Multi-level gene expression profiles affected by thymidylate synthase and 5-fluorouracil in colon cancer
BACKGROUND: Thymidylate synthase (TS) is a critical target for cancer chemotherapy and is one of the most extensively studied biomarkers for fluoropyrimidine-based chemotherapy. In addition to its critical role in enzyme catalysis, TS functions as an RNA binding protein to regulate the expression of...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1448211/ https://www.ncbi.nlm.nih.gov/pubmed/16584549 http://dx.doi.org/10.1186/1471-2164-7-68 |