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Comparison of P2X and TRPV1 receptors in ganglia or primary culture of trigeminal neurons and their modulation by NGF or serotonin

BACKGROUND: Cultured sensory neurons are a common experimental model to elucidate the molecular mechanisms of pain transduction typically involving activation of ATP-sensitive P2X or capsaicin-sensitive TRPV1 receptors. This applies also to trigeminal ganglion neurons that convey pain inputs from he...

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Detalles Bibliográficos
Autores principales: Simonetti, Manuela, Fabbro, Alessandra, D'Arco, Marianna, Zweyer, Marina, Nistri, Andrea, Giniatullin, Rashid, Fabbretti, Elsa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1448213/
https://www.ncbi.nlm.nih.gov/pubmed/16566843
http://dx.doi.org/10.1186/1744-8069-2-11