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Linking Splicing to Pol II Transcription Stabilizes Pre-mRNAs and Influences Splicing Patterns

RNA processing is carried out in close proximity to the site of transcription, suggesting a regulatory link between transcription and pre-mRNA splicing. Using an in vitro transcription/splicing assay, we demonstrate that an association of RNA polymerase II (Pol II) transcription and pre-mRNA splicin...

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Detalles Bibliográficos
Autores principales: Hicks, Martin J, Yang, Chin-Rang, Kotlajich, Matthew V, Hertel, Klemens J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450099/
https://www.ncbi.nlm.nih.gov/pubmed/16640457
http://dx.doi.org/10.1371/journal.pbio.0040147