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Linking Splicing to Pol II Transcription Stabilizes Pre-mRNAs and Influences Splicing Patterns
RNA processing is carried out in close proximity to the site of transcription, suggesting a regulatory link between transcription and pre-mRNA splicing. Using an in vitro transcription/splicing assay, we demonstrate that an association of RNA polymerase II (Pol II) transcription and pre-mRNA splicin...
Autores principales: | Hicks, Martin J, Yang, Chin-Rang, Kotlajich, Matthew V, Hertel, Klemens J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450099/ https://www.ncbi.nlm.nih.gov/pubmed/16640457 http://dx.doi.org/10.1371/journal.pbio.0040147 |
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