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PPARγ-independent induction of growth arrest and apoptosis in prostate and bladder carcinoma

BACKGROUND: Although PPARγ antagonists have shown considerable pre-clinical efficacy, recent studies suggest PPARγ ligands induce PPARγ-independent effects. There is a need to better define such effects to permit rational utilization of these agents. METHODS: We have studied the effects of a range o...

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Detalles Bibliográficos
Autores principales: Chaffer, Christine L, Thomas, David M, Thompson, Erik W, Williams, Elizabeth D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450298/
https://www.ncbi.nlm.nih.gov/pubmed/16519808
http://dx.doi.org/10.1186/1471-2407-6-53