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Identifying metabolic enzymes with multiple types of association evidence

BACKGROUND: Existing large-scale metabolic models of sequenced organisms commonly include enzymatic functions which can not be attributed to any gene in that organism. Existing computational strategies for identifying such missing genes rely primarily on sequence homology to known enzyme-encoding ge...

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Detalles Bibliográficos
Autores principales: Kharchenko, Peter, Chen, Lifeng, Freund, Yoav, Vitkup, Dennis, Church, George M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450304/
https://www.ncbi.nlm.nih.gov/pubmed/16571130
http://dx.doi.org/10.1186/1471-2105-7-177