Delayed functional maturation of natural regulatory T cells in the medulla of postnatal thymus: role of TSLP

BACKGROUND: Generation of functional CD4(+)CD8(-)CD25(+ )regulatory T cells (Treg) in the murine thymus depends on FoxP3. Removal of the thymus from neonatal mice has been shown to result in a multiple organ autoimmune disease phenotype that can be prevented by introducing the FoxP3(+ )Treg populati...

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Detalles Bibliográficos
Autores principales: Jiang, Qi, Su, Hua, Knudsen, Geoffry, Helms, Whitney, Su, Lishan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450317/
https://www.ncbi.nlm.nih.gov/pubmed/16579866
http://dx.doi.org/10.1186/1471-2172-7-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450317/
https://www.ncbi.nlm.nih.gov/pubmed/16579866
http://dx.doi.org/10.1186/1471-2172-7-6

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