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Delayed functional maturation of natural regulatory T cells in the medulla of postnatal thymus: role of TSLP
BACKGROUND: Generation of functional CD4(+)CD8(-)CD25(+ )regulatory T cells (Treg) in the murine thymus depends on FoxP3. Removal of the thymus from neonatal mice has been shown to result in a multiple organ autoimmune disease phenotype that can be prevented by introducing the FoxP3(+ )Treg populati...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450317/ https://www.ncbi.nlm.nih.gov/pubmed/16579866 http://dx.doi.org/10.1186/1471-2172-7-6 |