Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging

Herpes simplex virus type-1 expresses a heterodimeric Fc receptor, gE-gI, on the surfaces of virions and infected cells that binds the Fc region of host immunoglobulin G and is implicated in the cell-to-cell spread of virus. gE-gI binds immunoglobulin G at the basic pH of the cell surface and releas...

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Detalles Bibliográficos
Autores principales: Sprague, Elizabeth R, Wang, Chu, Baker, David, Bjorkman, Pamela J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450327/
https://www.ncbi.nlm.nih.gov/pubmed/16646632
http://dx.doi.org/10.1371/journal.pbio.0040148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450327/
https://www.ncbi.nlm.nih.gov/pubmed/16646632
http://dx.doi.org/10.1371/journal.pbio.0040148

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