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The molecular mechanism of DNA damage recognition by MutS homologs and its consequences for cell death response

We determined the molecular mechanism of cell death response by MutS homologs in distinction to the repair event. Key protein–DNA contacts differ in the interaction of MutS homologs with cisplatinated versus mismatched DNA. Mutational analyses of protein–DNA contacts, which were predicted by molecul...

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Detalles Bibliográficos
Autores principales: Salsbury, Freddie R., Clodfelter, Jill E., Gentry, Michael B., Hollis, Thomas, Scarpinato, Karin Drotschmann
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450329/
https://www.ncbi.nlm.nih.gov/pubmed/16648361
http://dx.doi.org/10.1093/nar/gkl238