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Fold Designability, Distribution, and Disease

Fold designability has been estimated by the number of families contained in that fold. Here, we show that among orthologous proteins, sequence divergence is higher for folds with greater numbers of families. Folds with greater numbers of families also tend to have families that appear more often in...

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Detalles Bibliográficos
Autores principales: Wong, Philip, Frishman, Dmitrij
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456317/
https://www.ncbi.nlm.nih.gov/pubmed/16680196
http://dx.doi.org/10.1371/journal.pcbi.0020040