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High-Resolution Recombination Patterns in a Region of Human Chromosome 21 Measured by Sperm Typing

For decades, classical crossover studies and linkage disequilibrium (LD) analysis of genomic regions suggested that human meiotic crossovers may not be randomly distributed along chromosomes but are focused instead in “hot spots.” Recent sperm typing studies provided data at very high resolution and...

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Detalles Bibliográficos
Autores principales: Tiemann-Boege, Irene, Calabrese, Peter, Cochran, David M, Sokol, Rebecca, Arnheim, Norman
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456319/
https://www.ncbi.nlm.nih.gov/pubmed/16680198
http://dx.doi.org/10.1371/journal.pgen.0020070