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Homologous recombination prevents methylation-induced toxicity in Escherichia coli

Methylating agents such as N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) and methyl methane sulfonate (MMS) produce a wide variety of N- and O-methylated bases in DNA, some of which can block replication fork progression. Homologous recombination is a mechanism by which chromosome replication can proc...

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Detalles Bibliográficos
Autores principales: Nowosielska, Anetta, Smith, Stephen A., Engelward, Bevin P., Marinus, M. G.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456334/
https://www.ncbi.nlm.nih.gov/pubmed/16670432
http://dx.doi.org/10.1093/nar/gkl222