The chrondoprotective actions of a natural product are associated with the activation of IGF-1 production by human chondrocytes despite the presence of IL-1β

BACKGROUND: Cartilage loss is a hallmark of arthritis and follows activation of catabolic processes concomitant with a disruption of anabolic pathways like insulin-like growth factor 1 (IGF-1). We hypothesized that two natural products of South American origin, would limit cartilage degradation by r...

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Detalles Bibliográficos
Autores principales: Miller, Mark JS, Ahmed, Salahuddin, Bobrowski, Paul, Haqqi, Tariq M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456997/
https://www.ncbi.nlm.nih.gov/pubmed/16603065
http://dx.doi.org/10.1186/1472-6882-6-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456997/
https://www.ncbi.nlm.nih.gov/pubmed/16603065
http://dx.doi.org/10.1186/1472-6882-6-13

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