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Optic cup and facial patterning defects in ocular ectoderm β-catenin gain-of-function mice

BACKGROUND: The canonical Wnt signaling pathway has a number of critical functions during embryonic development and, when activated aberrantly, in the genesis of cancer. Current evidence suggests that during eye development, regulation of Wnt signaling is critical for patterning the surface ectoderm...

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Detalles Bibliográficos
Autores principales: Miller, Leigh-Anne D, Smith, April N, Taketo, M Mark, Lang, Richard A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458322/
https://www.ncbi.nlm.nih.gov/pubmed/16539717
http://dx.doi.org/10.1186/1471-213X-6-14