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Optic cup and facial patterning defects in ocular ectoderm β-catenin gain-of-function mice
BACKGROUND: The canonical Wnt signaling pathway has a number of critical functions during embryonic development and, when activated aberrantly, in the genesis of cancer. Current evidence suggests that during eye development, regulation of Wnt signaling is critical for patterning the surface ectoderm...
Autores principales: | Miller, Leigh-Anne D, Smith, April N, Taketo, M Mark, Lang, Richard A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458322/ https://www.ncbi.nlm.nih.gov/pubmed/16539717 http://dx.doi.org/10.1186/1471-213X-6-14 |
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