Kinetics of double-chain reversals bridging contiguous quartets in tetramolecular quadruplexes

Repetitive 5′GGXGG DNA segments abound in, or near, regulatory regions of the genome and may form unusual structures called G-quadruplexes. Using NMR spectroscopy, we demonstrate that a family of 5′GCGGXGGY sequences adopts a folding topology containing double-chain reversals. The topology is compos...

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Detalles Bibliográficos
Autores principales: Mergny, Jean-Louis, De Cian, Anne, Amrane, Samir, da Silva, Mateus Webba
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458523/
https://www.ncbi.nlm.nih.gov/pubmed/16682446
http://dx.doi.org/10.1093/nar/gkl098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458523/
https://www.ncbi.nlm.nih.gov/pubmed/16682446
http://dx.doi.org/10.1093/nar/gkl098

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