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Kinetics of double-chain reversals bridging contiguous quartets in tetramolecular quadruplexes
Repetitive 5′GGXGG DNA segments abound in, or near, regulatory regions of the genome and may form unusual structures called G-quadruplexes. Using NMR spectroscopy, we demonstrate that a family of 5′GCGGXGGY sequences adopts a folding topology containing double-chain reversals. The topology is compos...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458523/ https://www.ncbi.nlm.nih.gov/pubmed/16682446 http://dx.doi.org/10.1093/nar/gkl098 |