Inferring Loss-of-Heterozygosity from Unpaired Tumors Using High-Density Oligonucleotide SNP Arrays

Loss of heterozygosity (LOH) of chromosomal regions bearing tumor suppressors is a key event in the evolution of epithelial and mesenchymal tumors. Identification of these regions usually relies on genotyping tumor and counterpart normal DNA and noting regions where heterozygous alleles in the norma...

Descripción completa

Detalles Bibliográficos
Autores principales: Beroukhim, Rameen, Lin, Ming, Park, Yuhyun, Hao, Ke, Zhao, Xiaojun, Garraway, Levi A, Fox, Edward A, Hochberg, Ephraim P, Mellinghoff, Ingo K, Hofer, Matthias D, Descazeaud, Aurelien, Rubin, Mark A, Meyerson, Matthew, Wong, Wing Hung, Sellers, William R, Li, Cheng
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458964/
https://www.ncbi.nlm.nih.gov/pubmed/16699594
http://dx.doi.org/10.1371/journal.pcbi.0020041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458964/
https://www.ncbi.nlm.nih.gov/pubmed/16699594
http://dx.doi.org/10.1371/journal.pcbi.0020041

Ejemplares similares