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Thrombin generation by activated factor VII on platelet activated by different agonists. Extending the cell-based model of hemostasis

BACKGROUND: Platelet activation is crucial in normal hemostasis. Using a clotting system free of external tissue factor, we investigated whether activated Factor VII in combination with platelet agonists increased thrombin generation (TG) in vitro. METHODS AND RESULTS: TG was quantified by time para...

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Detalles Bibliográficos
Autores principales: Altman, Raul, Scazziota, Alejandra Silvia, Herrera, Maria de Lourdes, Gonzalez, Claudio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459108/
https://www.ncbi.nlm.nih.gov/pubmed/16630353
http://dx.doi.org/10.1186/1477-9560-4-5